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The New England Journal of Medicine. Chung JH, Dewal N, Sokol E, Mathew P, Whitehead R, Millis SZ, Frampton GM, Bratslavsky G, Pal SK, Lee RJ, Necchi A, Gregg JP, Lara P Jr, Antonarakis ES, Miller VA, Ross JS, Ali SM, Agarwal N. Northbrook, IL: Astellas Inc. Avoid strong CYP2C8 inhibitors, as they can increase the plasma exposure to XTANDI. Despite treatment advancement in metastatic castration-resistant prostate cancer (mCRPC).

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D, FASCO, Professor and Presidential Endowed Chair of Cancer Research at Huntsman Cancer Institute, University of Utah, and global lead investigator for TALAPRO-2. As a global standard of care, XTANDI has shown efficacy in three types of prostate cancer that has received regulatory approvals for use in men with metastatic castration-resistant prostate cancer. PRES is a neurological disorder that can present with rapidly evolving symptoms including seizure, headache, lethargy, confusion, blindness, and other visual and neurological disturbances, with or without associated hypertension. If co-administration is necessary, increase the dose of XTANDI.

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